![]() ![]() The parameters studied were -thyroid gland weight, histopathology, histomorphometry thyroid peroxidase (TPO), 5'- deiodinase I (DI), sodium-potassium adenosine triphosphatase (Na+-K+-ATPase) activities serum total and free thyroxine (tT4, fT4), total and free triiodothyronine (tT3, fT3), thyroid stimulating hormone (TSH) levels. ![]() Adult male Wistar strain rats were subjected to calcium treatment at the doses of 0.5g%, 1.0g% and 1.5g% calcium chloride (CaCl2) for 60 days. "Certain epidemiological studies revealed correlation between hard water consumption (with high calcium) and thyroid size of the population, though the possible alterations in thyroid physiology upon calcium exposure are still inconclusive.
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